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Vessel Diameter Measurement in Intravital Microscopy

Jaesung Lee

In microcirculation studies, the blood vessel diameter is often measured to quantify the effects of various stimuli on circulation system. The vessel diameter is measured in intravital videos spanning several minutes, and The biological researchers have the burden of hand-measuring the diameter in hundreds of image frames. The goal of the automated tracking of vessel diameter is to measure accurately the vessel diameter in the intravital video microscopy.

The algorithm is based on feature tracking method, which tracks two seed points throughout the entire video microscopy. Our study using intravital and synthetic video shows that our automated algorithm to measure vessel diameter is both faster and more reliable than the manual measurement. [Lee, ISBI07]


Presentations and Publications

  1. J. Lee, A. Jirapatnakul, A. P. Reeves, W. Crowe, and S. Sarelius. Vessel Diameter Tracking in Intravital Microscopy Image Sequences. IEEE International Symposium on Biomedical Imaging: From Macro to Nano, pp. 360-363, April 2007.


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