VBMD

VisionX V4
NAME

vbmd − vertebral body closed surface segmentation and BMD measurements

SYNOPSIS

vbmd if= im= iv= vy= vz= ic= of= [ov=] [-d] [-v]

DESCRIPTION

vbmd first performs vertebral body segmentation (vvtbd) by separating the vertebral body from the posterior processes of the segmented vertebra based on the analysis of the image intensity profile. It then performs the closed surface segmentation of the vertebral body (vvtbdsf) by applying progressive surface resolution algorithm that was described in [SLYX16]. Finally, RIOs are extracted from the segmented vertebral bodies with closed surface as described in [SLJG18], and the bone mineral density (BMD) related statistics are computed (vbmdm) in the ROIs including: ave(average density in HU), std(standard deviation in HU), sk(skewness), kt(kurtosis), and vol(volume in mm^3).

[SLYX16]. Liu, S., Xie, Y. and Reeves, A.P., 2016. Automated 3D closed surface segmentation: application to vertebral body segmentation in CT images. International journal of computer assisted radiology and surgery, 11(5), pp.789-801.

[SLJG18]. Liu, S., Gonzalez, J., Zulueta, J., de-Torres, J.P., Yankelevitz, D.F., Henschke, C.I. and Reeves, A.P., 2018, February. Fully automated bone mineral density assessment from low-dose chest CT. In Medical Imaging 2018: Computer-Aided Diagnosis (Vol. 10575, p. 105750M). International Society for Optics and Photonics.

CONSTRAINT

The algorithm assumes the input im= contains segmented ribs, SCC, and vertebra (with anatomical labels).

OPTIONS

if=

input scan

im=

input organ map (ribs, SCC, and vertebra (with anatomical labels))

iv=

input seed coordinates for vertebra dividing planes in csv (label, mapValue, x, y, z per row)

vy=

input y component of the normal direction of SCC

vz=

input z component of the normal direction of SCC

ic=

input icosahedron model used for triangular mesh initialization

of=

output statistics of the measurements in csv (vidx, vol(mm^3), mean(HU), sd(HU), skewness, kurtosis), where vidx is the index for the vertebra (1 for T1, 2 for T2, 13 for L1 and -1 for C7).

ov=

output ROIs with anatomical labels for visualization.

-v

verbose operation

-d

debug mode

SEE ALSO

vvtbd(1), vvtbdsf(1), vbmdm(1)

AUTHOR

Shuang Liu