Pulmonary Nodule Analysis Applications

Several Image analysis applications are available on the system for the analysis of chest and cardiac CT images.

Image nodule detectors

vmonodule

This application runs the MONAI lung nodule detection algorithm

vtsnodule

Runs the TotalSegmentator (Bluemind) nodule detection algorithm

          

These applications have the following Syntax

                  <application>   [if=]<input>  [of=]output [od=<output-directory>] [-ic] [-csv]

Nodule csv file output:

The output of the nodule detectors is a csv file with the following columns

Column Heading

Contents

image

image-code of the analyzed image

nodule

a numeric nodule identifier (starts at 1)

x

x coordinate of nodule center in pixels

y

y coordinate of nodule center in pixels

z

z coordinate of nodule center in pixels

prob

probability that the entity is a pulmonary nodule

size

estimation of the diameter of the nodule in mm

xs

x-dimension extent of the nodule in pixels

ys

y-dimension extent of the nodule in pixels

xs

z-dimension extent of the nodule in pixels

 

The main program for providing input to the pulmonary nodule classifier is vnodext which has the following syntax:

                vnodext   [if=]<original-image> in=<nodule-csv-file> [of=][output directory] [-ic]

 

When the -ic option is specified the image original-image is specified by just the image-code. Note, this algorithm is define for a single image analysis only. A csv file from a batch run must be partitioned into individual image-code sets of rows for analysis.

The following experimental programs for nodule analysis are currently available:

vnodext

Extract the nodule regions from the original image and creates individual 32 x 32 x 32 images for malignancy evaluation. For classification the nodules are magnified by interpolation to occupy most of the space in the image. Actual unmagnified images can also be created for visualization.

vnodvis

Create a visualization version of the original image in which the regions of all detected nodules are clearly visible. Input parameters are similar to vnodext

vnview

The images that result from vnodext are windowed and tiled into a 6 x 6 grid for convenient visualization. The input is a 32 x 32 x 32 nodule region image created by vnodext.

vnnview

Apply vnview to all images in a directory